The A500 remains closed following a serious incident in the early hours of the morning.
Traffic is currently being diverted away from the area.
Eyewitnesses report seeing a forensics tent on the dual carriageway.
A Highways England spokesman said: “The A500 is closed southbound in Staffordshire between A53 and A52 near Hanley due to a serious collision.
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“Emergency services are on scene. Road users are being diverted via local routes at this time. Please allow extra time for your journey, should you be travelling in the area.”
StokeonTrentLive has contacted Staffordshire Police for further information and is awaiting a response.